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Jain studies how cells organize their contents. The Packard Fellowships in Science and Engineering are among the nation’s largest nongovernmental fellowships, designed to allow maximum flexibility in how the funding is used, according to the foundation’s Oct. 15 news release. Following a postdoctoral fellowship at the University of California San Francisco, he joins the MIT faculty in the Department of Biology as an assistant professor with an appointment as a member of the Whitehead Institute for Biomedical Research in the fall of 2018. Ankur Jain is an assistant professor in the Department of Biology and now a Thomas D. and Virginia W. Cabot Career Development Professor. Genesis 4 Super Smash Bros tournament last month. ATPase-driven oligomerization of RIG-I on RNA allows optimal activation of type-I interferon. View Ankur Jain’s profile on LinkedIn, the world's largest professional community. Ankur Jain explores the biology of RNA aggregation. During his postdoctoral research, Ankur Jain discovered that certain RNAs can form aggregates, clumping together and forming membrane-less droplets or ‘gels.’ This process, known as phase separation, has been widely studied in proteins but not in RNA. Thomas D. and Virginia M. Cabot Career Development Professor; Member, Whitehead Institute. Biophysicist Ankur Jain will join the Whitehead Institute as its newest member this coming September. There are instances of nucleotide repeats in our genome that occur even in the absence of repeat expansion disease genes. The lab is also investigating the role of RNA-DNA interactions in chromatin organization. This wikipedia page presents a series timeline into the far future (up to a billion years) for Earth, humanity, and astrological events. Jain uses a variety of biophysical approaches to understand how the RNA aggregates form, and how they can be disrupted to restore normal cell function. Assistant Professor of Biology; Member, Whitehead Institute. We're always interested in hearing about news in our community. Since 1988, the program has supported the blue-sky thinking of scientists and engineers with the belief that their research over time will lead to new discoveries that improve people’s lives and enhance our understanding of the universe, it said. How does the sequence of an RNA control its localization? 452.3563 ajain@wi.mit.edu. 2000 – 2003. Our lab develops new biochemical and biophysical techniques to investigate these compartments and to understand their dysfunction in human disease. Single-Molecule Analysis of Lipid-Protein Interactions in Crude Cell Lysates. Ankur has 7 jobs listed on their profile. An improved surface passivation method for single-molecule studies. Thomas D. and Virginia W. Cabot Career Development Professorship. “His insights are exciting, and the intellectual and scientific creativity he brings to his research is energizing.”. The Fellowships program was inspired by David Packard’s commitment to strengthen university-based science and engineering programs in the United States, the release said. ... Ist prize in Brain Sizzler event in Hi-Tech 2005 held in MIT, Moradabad. We study how molecules in a cell self-organize. Several genetic neuromuscular disorders such as myotonic dystrophy and amyotrophic lateral sclerosis are caused by expansions of nucleotide repeats in their cognate disease genes. How do repetitive sequences affect chromatin organization? RNA aggregation may also play a role in normal cellular function. (Packard.org photo). “Ankur brings an approach grounded in a combination of soft-matter physics and cell biology to help pioneer an important — potentially ground-breaking — way of investigating and understanding RNA aggregation and RNA-DNA interaction,” says David C. Page, Whitehead Institute director and member. Ankur Jain explores the biology of RNA aggregation. Students at MIT and NYU developed an AI bot that taught itself in two weeks to beat pro gamers! They are studying the RNA transcribed from the telomeric sequences in order to understand their structure and if they undergo phase separation similar to the one seen in repeat expansion diseases. JAIN LAB. Repetitive DNA sequences at the end of our chromosomes interact with proteins to form our telomeres, structures critical for chromosome maintenance. He earned a doctorate in biophysics and computational biology at University of Illinois at Urbana-Champaign in 2013, and received his bachelor’s degree (with honors) in biotechnology and biochemical engineering from Indian Institute of Technology Kharagpur in 2007. ... 2052 others named Ankur Jain are on LinkedIn. A class of neurological disorders called repeat expansion diseases, which includes amyotrophic lateral sclerosis (ALS) and fragile X syndrome, are marked by stretches of DNA nucleotide repeats in their cognate disease gene. While it is understood that protein aggregation is […] In addition, Jain will build on his specialized expertise in quantitative light microscopy to drive development of new imaging-based technologies. You have permission to edit this article. “I can’t wait to see what direction the work of these brilliant scientists and engineers will take. At the Whitehead Institute, Jain will continue his investigation into the properties of these RNA aggregates in order to learn how they form, what properties they possess, and how they could be disrupted to restore normal cellular processes. Our lab develops new biochemical and biophysical techniques to investigate these compartments and to understand their dysfunction in human disease. According to MIT, Jain joined Whitehead Institute and MIT in 2018, after conducting postdoctoral research in the lab of Ronald Vale at the University of California at San Francisco. Jain will use nuclear speckles — areas in the nucleus associated with pre-mRNA splicing — as a model for physiological RNA-protein granules.

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